Scientists are able to confirm hearing recovery by placing electrodes on the animals’ heads and playing sounds into their ears. Gene therapy has worked in experiments with deaf mice that lack the otoferlin protein. Representatives from both companies declined to say whether any participants have been given the gene therapy yet. ![]() ![]() Akouos plans to include up to 14 participants at hospitals in the US and Taiwan, and that study will last for two years. Decibel Therapeutics is enrolling up to 22 children in the US, UK, and Spain and will follow them for five years. In an emailed statement to WIRED, Akouos CEO Manny Simons wrote, “At the individual level, hearing loss can have a profound impact on cognitive development and psychiatric health.” (The company did not make a representative available for an interview.)īecause cochlear implants can damage the delicate hair cells of the inner ear, the companies running the current trials are seeking children who don’t have these devices.
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